Dry powder inhalers are environmentally preferable to metered-dose inhalers

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Metered-dose inhalers, dry powder inhalers, and transitions.

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Metered-dose inhalers and dry powder inhalers in aerosol therapy.

Inhaled drug delivery is an important part of the armamentarium of clinicians caring for patients with pulmonary disease. An increasing variety of metered-dose inhalers and dry powder inhalers are becoming available. This has been driven by the development of new formulations and the impending ban on chlorofluorocarbon propellants. The result is a proliferation of devices, resulting in a confus...

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Inhalation therapy with metered-dose inhalers and dry powder inhalers in mechanically ventilated patients.

Pressurized metered-dose inhalers (pMDIs) are commonly employed for administering bronchodilator aerosols to mechanically ventilated patients. Although it is feasible to employ dry powder inhalers in ventilator circuits, the presence of humidity in the ventilator circuit could reduce their efficiency. A complex array of factors influence drug delivery from pMDIs during mechanical ventilation, a...

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Assessing dry powder inhalers

To enable what would otherwise be impractical, invasive and potentially dangerous testing, and to remove the huge variation and costs associated with human subjects, it is common practice to test inhalation devices and formulations using in vitro test apparatus. Industry standard test conditions and relevant parameters have been devised and published by the regulatory authorities and within the...

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Dry powder inhalers: an overview.

Dry powder inhalers (DPIs) are a widely accepted inhaled delivery dosage form, particularly in Europe, where they currently are used by a large number of patients for the delivery of medications to treat asthma and chronic obstructive pulmonary disease. The acceptance of DPIs in the United States after the slow uptake following the introduction of the Serevent Diskus in the late 1990s has been ...

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ژورنال

عنوان ژورنال: Canadian Medical Association Journal

سال: 2020

ISSN: 0820-3946,1488-2329

DOI: 10.1503/cmaj.75949